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Lesson Plans Inc. is a curriculum community for high school & middle school    
science teachers. Included in the macromolecule content area are carbohydrate    
experiments, protein labs, macromolecule projects, dehydration synthesis    
activities, pH demos, acid and base worksheets, and biochemistry exam / test    
/ quiz questions. Some lesson plan topics include macromolecules, carbohydrates,    
proteins, lipids, nucleic acids, water molecules, acids and bases, and more.    
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Macromolecule Lesson Plans

Protein     Organic compounds & molecular biology lesson plans designed for high school and middle school science teachers are downloadable here.  Click the titles below to see a list of lessons for each category. Free macromolecule lesson plans include:

Proteins Lesson Plans

  • Polypeptides - 20 different amino acids, peptide bonds.
  • Amino Acids - amino group, carboxyl group, side groups.
  • Shape - folding chains of amino acids, hydrogen bonds, shape determines function, primary, secondary, plated sheet, alpha helix, tertiary, quaternary structures.
  • Functions - enzymes, structure, movement, energy source, transport, immunity.
  • Food Types - dairy, eggs, fish, grains, legumes, meat, nuts, poultry, seeds, vegetables.

Carbohydrate Lesson Plans

  • Carbohydrates - monosaccharides, disaccharides, polysaccharides.
  • Monosaccharides - glucose sugar, fructose.
  • Disaccharides - sucrose sugar, lactose, maltose.
  • Polysaccharides - starch, glycogen, cellulose.
  • Food Types - sugar, breads, cereal, fruits, milk, pasta, vegetables.
  • Fiber Types - apple, baked potato, barley, bran cereal, dried beans, pear.

Lipid Lesson Plans

  • Lipids - fats, lipoproteins, phospholipids, sterols, triglycerides.
  • Lipoproteins - VLDL very low density lipoprotein, LDL low density lipoprotein, HDL high density lipoprotein.
  • Phospholipids - lipid bilayer, 2 fatty acid tails, one glycerol, one phosphorus acid chain.
  • Sterols - steroids, cholesterol.
  • Triglycerides - saturated fatty acids, unsaturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, trans-fatty acids.
  • Food Types - butter, cheese, meats, milk, nuts, oils.
  • Saturated Fat Types - butter, coconut oil, lard, palm oil.
  • Unsaturated Fat Types - avocados, Canola oil, fish, olive oil, sunflower oil.
  • Cholesterol Types - eggs, dairy, fish, meats, poultry.

Nucleic Acids Lesson Plans

  • Polymers - DNA, RNA.
  • Nucleotides - hydrogen bonds, phosphate group, deoxyribose and ribose pentose sugars, nitrogen bases.
  • Structure - double helix, mRNA, tRNA, rRNA.

Acids and Bases Experiments

  • pH - common acids and bases.
  • Acids - acidic solutions, common acids, hydrogen ions.
  • Bases - alkaline solutions, common bases, hydroxide ions.
  • Buffers - weak acid or base with its conjugate base or acid, keep pH constant.

Biochemistry Basics Lesson Plans

  • Organic molecules - monomers and polymers of macromolecules
  • Inorganic molecules - water , carbon dioxide
  • Dehydration synthesis - loss of an H2O molecule, making of polymers.
  • Hydrolysis - addition of an H2O molecule, splitting of polymers into monomers.
  • Atoms - protons, neutrons, electrons, orbital shells.
  • Elements - periodic table, carbon, hydrogen, oxygen, nitrogen.
  • Compounds - chemical bonds.
  • Covalent Bonding - sharing of electrons.
  • Ionic Bonding - gaining or losing electrons to form ions.
  • H2O - hydrogen bonds, polarity of water, cohesion, adhesion.

Lesson Plans by Subject

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Macromolecule Concepts

A great biochemistry experiment is where students use common household acids and bases to test for pH.  A dehydration synthesis activity lets students combine paper molecules and form water.  Biochemistry projects include researching different proteins, their amino acid structure, and their functions. Molecular biology worksheets and exam / test / quiz questions also provide help with evaluating the student’s progress.

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