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Lesson Plans Inc. is a curriculum community for science teachers. High school, middle     
school, and elementary school curriculums include DNA extraction experiments,    
DNA storybook projects, protein synthesis activities, double helix    
demos, and DNA and RNA exam / test / quiz questions. Some lesson plan    
topics include DNA replication, DNA structure, cancer, biotechnology,     
transcription, translation, & gene regulation.    
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DNA & RNA Lesson Plans

Cell     DNA and RNA Proteins synthesis lesson plans designed for high school, middle school, and elementary school science teachers are downloadable here. Lesson Plans Inc. offers many great science lessons. Click the titles below to see a list of lessons for each category. Free DNA & RNA lesson plans include:

DNA and RNA Structure Lesson Plans

  • Shape - double helix, 5' OH group and 3' phosphate group.
  • DNA Nucleotide - deoxyribose sugar, phosphate group, dna nitrogen base, hydrogen bonds.
  • DNA Nitrogen Bases - adenine, thiamine, guanine, cytosine, purines, pyrimidines.
  • RNA Nucleotide - ribose sugar, phosphate group, rna nitrogen bases.
  • RNA Nitrogen Bases - adenine, uracil, guanine, cytosine.
  • Semi-Conservative Replication - complementarity, leading strand, lagging strand, replication fork, 5' to 3'.
  • DNA Replication Enzymes - DNA helicase, DNA polymerase, Okazaki fragments, DNA ligase.

Protein Synthesis Lesson Plans

  • Central Dogma - gene expression follows a specific order.
  • Transcription - RNA polymerase, initiation, elongation, termination, promoter regions, introns, exons, codons, mRNA, transcribe template strand.
  • Translation - ribosome (rRNA and protein), anticodons, tRNA, initiation, elongation, termination, A-site, P-site, amino acids, polypeptide chain, start codon, stop codon.

Biotechnology Lesson Plans

  • Recombinant DNA - plasmids, bacterial DNA, cloning vector, restriction enzymes, screening, gene cloning, DNA ligase, electroporation, bacterial culture growth.
  • PCR - polymerase chain reactions, synthetic oligonucleotide primers, pcr amplification, in vitro, heating, cooling, DNA polymerase, reheating.
  • GEL Electrophoresis - restriction enzymes, polar DNA, DNA fragments, DNA ladder, agarose gel, lane, band.
  • Southern Blot - DNA fragments, gel electrophoresis, probe.
  • Northern blot - identify RNA fragments.
  • Western blot - identify proteins.
  • Transgenic Bacteria - foreign DNA, insulin, growth hormone, clotting factors.
  • Transgenic Animals - growth hormone genes, resistance to bacterial infections, proteins.
  • Transgenic Plants - 52% soy and 25% corn are transgenic in US, genetically modified food, natural insecticdes, resist chemicals.
  • Gene Cloning - Dolly, fuse mammary cells with egg cells without DNA, electric shock, in vitro, implanted into surrogate mother, gentically identical sheep.
  • Human Genome Project - human nucleotide sequence, map genes on chromosomes,

Mutations Lesson Plans

  • Gene Mutations - point mutations, base-pair substitution, silent mutations, transition mutation, transversion mutations, missense mutations, nonsense mutations, frameshift mutations, insertion, deletion, revertant.
  • Chromosomal Mutations - deletion, duplication, inversion, translocation.
  • Genetic Disorders - nondisjunction, down syndrome or trisomy 21, trisomy X or XXX syndrome, Klinefelter's syndrome or XXY , Edwards Syndrome or trisomy 13.

Gene Regulation Lesson Plans

  • Prokaryotes - operon, promoter, operator, repressor protein, lac operon.
  • Negative Gene Regulation - repressible operons, corepressors, inducible operons, inducer.
  • Positive Gene Regulation - activator, allosteric site.
  • Eukaryotes - modify chromatin, control elements, steroid hormones, regulatory proteins, TATA box, gene dosage, gene amplification.

Lesson Plans by Subject

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DNA Lesson Concepts

The DNA extraction lab lets students extract DNA from either their cheek cells or strawberries. Another great DNA experiment is gel electrophoresis. An example DNA activity lets students build a giant double helix and then try to model super coiling. Another activity is about protein synthesis and how cell DNA, mRNA, rRNA, tRNA, and amino acids are used to make proteins. DNA projects include writing a DNA replication storybook for little kids. Genetic worksheets and exam / test / quiz questions also provide help with evaluating the student's progress.

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These lessons may be freely copied and used in a classroom but they remain the copyrighted property of the author.